General Description of Spinal Diseases

 

Disc Disease

Dr. Epstein has written extensively on disc herniations involving the spine. Disc herniations are defined as an extrusion (popping out) of the cushion between the vertebral bodies. When discs herniate in the neck, they may compress the cervical spinal cord (central), and/ or nerve roots (off to the side). Nerve root compression can produce numbness, tingling or weakness, while spinal cord compression may result in the loss of sensation, weakness in the legs, or even severe paralysis. Only a subset of patients with disc herniations may require surgery. When these operations are required they can be performed from the front or back of the neck (cervical), mid back (thoracic), or lower back (lumbar spine).

 

Epstein NE, Epstein JA: Lumbar intervertebral disc herniation teenage children: Recognition and management of associated anomalies. Spine, 9(4): 427-423,1984

 

Epstein NE, Epstein JA, Carras R, Hyman RA, Vishnubakhat SM: Far lateral disc hernia ion: diagnosis and surgical management. Neuron - Orthopedics (Springer - Vela), 1(1): 37-44, 1986.

 

Epstein NE, Syrquin M, Epstein JA, Decker RE: Intradural disc herniations in the cervical, thoracic, and lumbar spine: Report of three cases and review of the literature. J Spinal Disord, 3(4): 396-403, 1990

 

Epstein NE, Epstein JA, Carras, Hyman R: Far lateral disc herniations and associated structural abnormalities: Evaluation of 60 patients and the comparative value of CT, MRI, and Myelo -CT in the diagnosis and management. Spine, 15(6): 534-539, 1990

 

Epstein NE, Epstein JA: Limbus vertebral fractures of the lumbar spine and spinal stenosis in five adolescents with further evaluation of Type III fractures. Neuro - Orthopedics (Springer-Verlag), 9: 33-52, 1990

 

Epstein NE, Syrquin M, Epstein JA, Decker RE: Intradural disc herniations in the cervical, thoracic, and lumbar spine: Report of three cases and review of the literature. J Spinal Disord, 3(4): 396-403, 1990

 

Epstein NE, Epstein JA: Limbus lumbar vertebral fractures in 27 adolescents and adults. Spine 16(8): 962-966, 1991

 

Epstein NE: Lumbar surgery for 56 limbus fractures emphasizing non -calcified Type III lesions. Spine, 17 (12): 1489-1496, 1992

 

Epstein NE, Epstein JA: Far lateral lumbar disc herniations. In Neurosurgical Operative Atlas, SS Rengachary, R Wilkins (eds), AANS Publications Committee, Vol. 5: 185-197, 1996

 

Epstein NE:  Far lateral and foraminal disc herniations. In Textbook Of Neurological Surgery, Batjer H, Loftus C (eds), Lippincott-Raven (pub), Philadelphia, PA, (in press)

 

Epstein NE: A review of laminoforaminotomy for the management of lateral and foraminal cervical disc herniations or spurs, Surgical Neurology 57(4): 226, 2002

 

Epstein NE: Anterior dynamic plates in complex cervical reconstructive surgeries. Journal of Spinal Disorders, 15(3): 221-227, 2002

 

Epstein NE: Anterior cervical dynamic ABC plating with single level corpectomy and fusion in 42 patients. Spinal Cord, 41: 153-158, 2003

 

Spinal Stenosis or Narrowing of the Spinal Canal

Spinal stenosis is the fancy term for narrowing of the spinal canal. You can be born with a narrowed spinal canal (congenital stenosis), or may develop arthritic changes as you age (acquired stenosis) which narrow your spinal canal. In the older population, spinal stenosis is much more common than disc disease. Arthritic changes may include calcified discs, calcified ligaments, calcified facet joints. Narrowing (stenosis) in the neck (cervical), mid back (thoracic), or lower back (lumbar spinal canal) may compress nerve tissue and produce numbness, tingling, weakness, or paralysis. The treatment includes operations from the front or back of the spine at any of these levels.

 

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Cervical Stenosis

 

Epstein NE, Epstein JA, Carras R, Vishnubhkat, SM, Hyman R: Co-existing cervical and lumbar spinal stenosis: Diagnosis and management. Neurosurgery, 15(4): 489-496, 1984.

 

Epstein NE, Epstein JA: Individual and coexistent lumbar and cervical spinal stenosis: diagnosis and surgical management. In Spine; State of the Art Reviews, Emery Hopp (ed), Hanley and Belfus (pub), Vol. 1(3): 401-420, 1987

 

Epstein NE, Epstein JA: Cervical spine stenosis. In Principles of Orthopedic Practice, Roger Dee, (ed), McGraw Hil l (pub), New York, Vol. 2 Chapter 57-Section B: 982-987, 1988

 

Epstein NE, Epstein JA, Carras R: Cervical spondylosis, stenosis, and myeloradiculopathy in patients over 65:  Diagnostic techniques and management. Neuro-Orthopedics (Springer-Verlag), 6(1): 13-32,1988

 

Epstein NE, Epstein JA, Carras R: Coexisting cervical spondylotic myelopathy and bilateral carpal tunnel syndromes. J Spinal Disorders, 2(1) 36 - 42, 1989

 

Epstein NE, Blanck R, Epstein JA: Problems in the diagnosis of coexisting cervical spondylotic myelopathy in the presence of multiple sclerosis: Report of 5 cases. Neuro-Orthopedics (Springer-Verlag), 10: 15-26, 1990

 

Epstein NE, Epstein JA: Operative management of cervical spondylotic myelopathy: technique and results of laminectomy. In The Cervical Spine -Third Edition, Clark CR (ed), Lippincott-Raven (pub), Philadelphia, Chapter 62: 829-838, 1998

 

Lumbar Stenosis

Epstein NE, Epstein JA, Carras R, Lavine LS: Degenerative spondylolisthesis with an intact neural arch: A review of 60 cases with an analysis of clinical findings and the development of surgical management. Neurosurgery, 13(5): 555-561,1983

 

Epstein JA, Epstein NE: Chapter: Lumbar spondylosis and spinal stenosis. In Neurosurgery, Robert H Wilkins, and Setti S. Rengachery (eds), McGraw Hill  (pub), New York, Pt IX, 94, 1985.

 

Epstein NE, Epstein JA: Surgery of the lumbar spine: lumbar spinal stenosis. In The Lumbar Spine, Camins MB, O’Leary PF (eds), Raven Press, New York, 149-161, 1987

 

Epstein NE, Schwall G: Thoracic spinal stenosis: diagnostic and treatment challenges. J Spinal Disord, 7(3): 259-269, 1994

 

Epstein NE, Epstein JA: Lumbar spinal stenosis. Neurological Surgery, 4th Edition, Youman JR (ed), Dunsker S (Section Editor), W.B. Saunders (pub), Philadelphia, Vol. 3, Chapter 106: 2390-2415, 1996

 

Epstein NE, Epstein JA: Lumbar decompression for spinal stenosis; surgical indications and techniques with and without fusion. In The Adult Spine, Principles And Practice - Second Edition, Frymoyer, John W  (ed), Lippincott - Raven (pub), Philadelphia, Chapter 97, Vol. II: 2055-2088, 1997

 

Epstein NE: Surgical management of lumbar stenosis: decompression and indications for fusion. Neurosurg Focus  3(2): Article 1: 1-14, August 1997

 

Epstein NE: Clinical Controversy: lumbar spinal stenosis. Surgical Neurology, 50:3-10, 1998

 

Epstein NE: Diagnosis of Epidural Lipomatosis in the Lumbar Spine: Report of 3 Cases. The Spine Journal (in press 2004)

 

Epstein NE: Section on degenerative lumbar spinal stenosis. In Youman’s Neurological Surgery, 5th Edition, Richard Winn (ed), W.B. Saunders, Philadelphia PA, (in press)


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Cervical and Lumbar Stenosis Surgery


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Instability (Too Much Movement Between The Bones)

 When there is too much motion between the bones of the spine (vertebral bodies) the excess motion can lead to pain, compression of the nerve tissue, and nerve damage. In the neck (cervical spine) and lower back (lumbar spine) instability or a “slip” can be seen on X-rays taken with the patient bending forward and backward. More long-standing slippage can be seen on regular X-rays, and MR or CT scans. Slips can be due to arthritic changes in the bones and ligaments, previous injury, or can follow operations. Operations performed to “stabilize” the slip are called fusions. Fusions can be performed from the front or back of the neck (cervical spine: anterior diskectomy, corpectomy, or circumferential surgery), mid back (thoracic spine), or lower back (microscope assisted diskectomy/laminotomy, laminectomy [non-instrumented, instrumented fusions].

 

Epstein NE: Primary fusion for the management of “unstable” degenerative spondylolisthesis. Neuro - Orthopedics (Spinger-Verlag), 23:45-52,1998

 

Epstein NE: Laminectomy with posterior wiring and fusion for cervical OPLL, spondylosis, OYL, stenosis, and instability:  A study of 5 patients.  J Spinal Disord 12: 461-466, 1999

 

Epstein NE: Technical Note: Unilateral posterior resection of cervical disc and spondylostenosis with contralateral fusion for instability, Surgical Neurology 56:

256-258, 2001

 

Epstein NE: Cervical laminectomy with or without posterior wiring and fusion or laminoplasty for the management of spondylostenosis and ossification of the posterior longitudinal ligament, Surgical Neurology, 58: 194-208, 2002

 

Epstein NE: Cervical laminectomy with or without posterior wiring and fusion or laminoplasty for the management of spondylostenosis and ossification of the posterior longitudinal ligament, Surgical Neurology, 58: 194-208, 2002

 

Epstein NE: Anterior cervical dynamic ABC plating with single level corpectomy and fusion in 42 patients. Spinal Cord, 41: 153-158, 2003

 

Epstein NE: An analysis of combined Inductive-Conductive Matrix and autologous bone graft in 61 posterior cervical fusions. Spinal Surgery 17(1): 1-6, 2003

 

Epstein NE: Fixed versus dynamic plate complications following multilevel anterior cervical corpectomy and fusion with posterior stabilization. Spinal Cord 41: 379-84,

  2003

 

Epstein NE, Silvergleide RS: Documenting fusion following anterior cervical surgery: A comparison of roentgenogram versus two-dimensional computed tomographic findings. J Spinal Disorders & Tech 16(3): 243-7, 2003

 

Epstein NE: Circumferential cervical surgery for Ossification of the Posterior Longitudinal Ligament: A Multianalytic outcome study. Spine, 29 (12):1340-1345, 2004

 

Epstein NE: Lumbar Synovial Cysts: a review of diagnosis, surgical management, and outcome assessment. J Spinal Disord Tech. 2004 Aug;17(4):321-5.

 

Epstein NE. Posterior Cervical Fusion Utilizing A Modified “Screwless” Vertex System  A Preliminary Report in 8 Patients. Spinal Surgery; 18(2): 63-70, 2004

 

Epstein NE. Dynamic Anterior Cervical  Plates for Multilevel  Anterior Corpectomy and Fusion With Simultaneous Posterior Wiring and Fusion: Efficacy and Outcomes.Spinal Cord (in press 2005)

 

Epstein NE: Complications and Outcome in Dynamic Plated Single Level Anterior Corpectomy and Fusion Including Two Level Complete Diskectomies. The Spine Journal (Submitted 2005)

 

Ossification of the Posterior Longitudinal Ligament (OPLL)

The posterior longitudinal ligament is located in front of the nerve tissue in the neck (cervical), mid back (thoracic), and lower back (lumbar spine). In some patients, this ligament can become calcified (ossified). Ossification of this posterior longitudinal ligament [OPLL] can compress the spinal cord or nerve roots in the spinal canal. It is most frequently found in the neck (cervical). OPLL can produce numbness, tingling, weakness, and even paralysis. Operations performed to remove OPLL can be extensive. If performed in front of the neck, it may require the removal of several vertebral bodies, the placement of a graft and plate, followed by fusion of the back of the neck (circumferential surgery). In some other patients, surgery from the back of the neck (laminectomy with/without fusion) can be performed. Many patients demonstrate significant postoperative improvement.

 

Epstein NE, Epstein JA: Simultaneous ossification of the posterior longitudinal ligament in the cervical and lumbar spinal canal. Neuro-Orthopedics (Springer-Verlag),  8: 45-53, 1989

 

Epstein NE: Diagnosis and surgical management of ossification of the posterior longitudinal ligament. Contemporary Neurosurgery, 22: 1-6, 1992

 

Epstein NE: Ossification of the Posterior Longitudinal Ligament: diagnosis and surgical management. Neurosurgical Quarterly, 2(3): 223-241, 1992

 

Epstein NE: Advanced cervical spondylosis with ossification into the posterior longitudinal ligament and resultant neurologic sequelae. J Spinal Disord,  9(6): 477-484, 1996

 

Epstein NE: Ossification of the posterior longitudinal ligament. In OPLL: Ossification of the Posterior Longitudinal Ligament, Yonenobu K, Sakou T, Ono K (eds), Springer-Verlag, Tokyo, Japan, 85-93, 1997

 

Epstein NE, Epstein JA: The surgical management of ossification of the posterior longitudinal ligament (OPLL).  Harefuah ( Israeli Medical BI-Weekly Journal honoring Aharon Beller M.D.),  Moshe Feinsod M.D. (ed),  67-74, 1997

 

Epstein NE: Ossification of the yellow (OYL) ligament and spondylosis and or ossification of the posterior longitudinal (OPLL) ligament of the thoracic and lumbar spine. J Spinal Disord 12(3): 250-256, 1999

 

Epstein NE: Simultaneous cervical diffuse idiopathic skeletal hyperostosis and ossification of the posterior longitudinal ligament resulting in dysphagia or myelopathy in two geriatric North Americans. Surgical Neurology 53(5): 427-31, 2000

 

Epstein NE:  Identification of ossification of the posterior longitudinal ligament extending through the dura on preoperative CT examination of the cervical spine.  Spine, 26(2): 182-186, 2001

 

Epstein, NE: In-Vitro Characteristics of Cultured Posterior Longitudinal Ligament Tissue, Spine 27(1): 56-58, 2002

 

Epstein NE: Review article: diagnosis and surgical management of cervical ossification of the posterior longitudinal ligament, The Spine Journal 2: 436-449, 2002

 

Epstein NE: Ossification of the cervical posterior longitudinal ligament: A review. Neurosurgical Focus 13(2): 1-10, 2002

 

Epstein NE: Familial Ossification of the Posterior Longitudinal Ligament Found in 4 North American Families. Spinal Surgery; 18(2): 57-62, 2004

 

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Spinal Tumors (Growths on the Spine)

Tumors affecting the spine can include benign (non-cancerous) tumors. They can be located in the bones, in the spinal cord itself, or outside of the cord.

 

Tumors in the Nerve Tissue of the Cord (Intramedullary): Tumors originating within the spinal cord itself include benign astrocytomas, benign ependymomas, and occasionally malignant gliomas or mestastases.

 

Epstein F, Epstein NE: Surgical management of “holocord” intramedullary spinal cord astrocytomas in children. J Neurosurg, 54(6): 829-832, 1981

 

Epstein NE, Epstein F, Allen J: Intractable facial pain associated with ganglioglioma of the cervicomedullary junction: A case report. Neurosurgery 10(5): 612-616, 1982

 

Epstein NE, Buchar S, Gavin R, Hyman RA, Zito J: Failure to diagnose conus ependymomas by magnetic resonance imaging. Spine, 14(1): 134-137, 1989

 

Epstein NE, Frank I: Chronic dysphagia, vomiting, and gastroesophageal reflex as manifestations of a brain stem glioma. Pediatric Neuroscience, 15(5): 265-268, 1989

 

Meningiomas: These are usually (95%) benign tumors originating from the covering of the nerve tissue (dura). They are found mostly in the neck (cervical) or mid back (thoracic) spinal canal. MR studies performed with dye (Gadolinium DTPA) best demonstrate these tumors. CT examinations can evaluate the degree of calcification while telling you about the surrounding bones. Many of these tumors can be completely removed, often from the back of the spine.

 

Epstein NE. Clear Cell Meningioma of the Cauda Equina in an Adult. A Case Report and Literature Review. J Spinal Disord and Tech (2004)

 

Neurofibromas: These are tumors that originate from specialized cells, which surround nerves (Schwann cells). They too are typically benign, but are found throughout the neck (cervical), mid back (thoracic), and lower back (lumbar spinal canal). Complete excision is feasible in the majority of cases, while a small subset may not be fully removable. Again, a small subset of these tumors may prove malignant, requiring additional radiation and/or chemotherapy.

 

Epstein NE: Clinical Opinion: Resection of massive retroperitoneal tumor extending into L5 vertebral body: Controversies in surgical management. J Spinal Disord, 10(2): 176-181, 1997

 

Benign Bone Tumors: Benign tumors originating in the bone include osteomas which may become malignant. Others include aneurismal bone cysts.

 

Epstein NE, Benjamin V, Pinto R, Budzilovich G: Benign osteoblastoma of a thoracic vertebra: Case Report. J Neurosurg, 53(5): 710-713, 1980

 

Surgery from the Front of the Neck


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Anterior Cervical (Neck) Diskectomy and Fusion For 1 Level Disc/Arthritis

 Operations can be done from the front of the neck (cervical spine) to remove disc herniations. First, a horizontal incision is made in the neck  (side to side in a wrinkle). Once the front of the spine is exposed, an X-ray is taken on the operating table to confirm the operative level. Microinstruments are used under an operating microscope to remove the disc and arthritic tissue (spur, spondylosis arthrosis). A fusion is next performed with a bone graft. The patient’s bone (autograft) is taken from the hip (iliac crest: not the hip joint but the curved bone of the pelvis). The patient’s bone heals better and faster in most studies than cadaver (allograft) bone. A titanium plate is placed over the bone graft to keep it in place. An X-ray taken on the operating table confirms placement of the bone graft and plate. A drain is placed in the neck and the wound is closed. At the end of the operation, patients awaken in a neck brace (CTO: cervical thoracic orthosis), are examined (to make sure they are OK), and are brought to the recovery room. A CT scan of the neck (cervical spine) performed the night after surgery check graft/plate placement. Patients are transferred for observation to the intensive care unit (older patients) or the step down unit. Most patients are discharged within 2-3 days, depending on their needs.

 

Epstein NE, Syrquin M, Epstein JA, Decker RE: Intradural disc herniations in the cervical, thoracic, and lumbar spine: Report of three cases and review of the literature. J Spinal Disord, 3(4): 396-403, 1990

 

Epstein NE: Anterior cervical diskectomy and fusion without plate instrumentation in 178 patients.  J Spinal Disord 13: 1-8, 2000

 

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Anterior Cervical (Neck) Corpectomy and Fusion For 1 Level Discs/Arthritis

Excision of two adjacent discs may also require removal of the intervening vertebral body if arthritic changes extend behind that body (bone). This operation is similar to that described for the 1 level diskectomy/fusion but requires more extensive decompression (removal of 2 discs and arthritis) with a longer graft obtained from the patient’s hip (iliac crest). Arthritis is removed with diamond drills and microinstruments under the operating microscope with monitoring the nerve potentials of the spinal cord (SSEPs) and nerves (EMGs).

 

Epstein NE: Reoperation Rates For Acute Graft Extrusion and Pseudarthrosis Following One Level Anterior Corpectomy and Fusion With and Without Plate Instrumentation: Etiology and Corrective Management. Surgical Neurology 56: 73-81, 2001

 

Epstein NE: Anterior dynamic plates in complex cervical reconstructive surgeries. Journal of Spinal Disorders, 15(3): 221-227, 2002

 

Epstein NE: Delayed iliac crest autograft fractures following plated single level anterior corpectomy with fusion. J Spinal Disord 15(5): 420-424, 2002

 

Epstein NE: Can recurrent pain be a signal of delayed autograft strut fracture following anterior cervical surgery? A radiographic correlation. Spinal Surgery (Japan) 16(3):

   197-205, 2002

 

Epstein NE: Anterior cervical dynamic ABC plating with single level corpectomy and fusion in 42 patients. Spinal Cord, 41: 153-158, 2003

 

Epstein NE: Does donor site reconstruction affect postoperative pain following single level anterior corpectomy with fusion? J Spinal Disord Tech 16(1):20-26, 2003

 

Circumferential Surgery (Front/Back) for Multiple Level OPLL/Arthritis

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Multilevel Anterior Cervical (Neck) Corpectomy and Fusion for OPLL/Arthritis

Patients with arthritis, and particularly, multiple level OPLL, may require the removal of several vertebral bodies (bones) of the neck (cervical spine). The approach from the front of the neck requires a longer horizontal incision. Intraoperative X-rays are similarly obtained to confirm the level of surgery after retractors (instruments to keep the tissues apart) are placed. Diamond drills, microinstruments, an operating microscope, and spinal cord monitoring are critical to successfully remove OPLL. Here, usually, a long, straight cadaver (allograft) graft is required to span multiple levels; a hip graft here is usually too curved and short. A longer titanium plate is placed over the graft. To reinforce and help prevent these larger grafts/plates from coming out, under the same anesthesia, a fusion from the back of the neck is performed.

 

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Multilevel Posterior Cervical (Neck) Fusion (Back) for OPLL/Arthritis

Fusions performed from the back of the neck to stabilize multilevel anterior (front) cervical (neck) operations, utilize a rod/eyelet/braided titanium cable system wired to the bones in the back of the neck (spinous processes). These fusions require the use of bone graft taken from the patients’ hip (autograft not from the hip joint but the iliac crest).

 

Epstein NE: The surgical management of ossification of the posterior longitudinal ligament in 51 patients. In The Yearbook of Neurology and Neurosurgery, RH Wilkins (ed), Mosby (pub), New York, 470, 1995

 

Epstein NE: Cervical ossification of the posterior longitudinal ligament. In Neurosurgery-Second Edition, Wilkins RH,  Rengachary Ss(eds), McGraw - Hill (pub), New York,  Vol. III, Chapter 383: 3781-3787, 1996

 

Epstein NE: Circumferential surgery for the management of ossification of the posterior longitudinal ligament. J Spinal Disord, 11(3): 200-207, 1998

 

Epstein NE: The value of anterior cervical plating in preventing vertebral fracture and graft extrusion following multilevel anterior cervical corpectomy with posterior wiring/fusion: Indications, results, and complications.  J Spinal Disord 13: 9-15, 2000

 

Epstein NE: Anterior Approaches To Cervical Spondylosis and OPLL: Review of

Operative Technique and Assessment of 65 Multilevel Circumferential Procedures. Surgical Neurol, 55(6): 313-324, 2001

 

Epstein NE, Hollingsworth R, Nardi D, Singer J: Can airway complications following multilevel anterior cervical surgery be avoided? J Neurosurg  ( Spine 2) 94: 185-188, 2001

 

Epstein NE: A comparative analysis of plate/graft failure with correction following

   circumferential cervical spinal surgery, Spinal Surgery 16(1): 1-8, 2002

 

Epstein NE: Chapter 43: Ossification of the Posterior Longitudinal Ligament of the Cervical Spne: Clinical, Neurodiagnostic, and Circumferential Surgical Management, p. 575-603 In Omurilik ve Omurga Cerrahisi, 1st Edition, M Zileli, A.F. Ozer (Eds),  Tpian A.S., Medikon A.S., 2002

 

Epstein NE: An analysis of combined Inductive-Conductive Matrix and autologous bone graft in 61 posterior cervical fusions. Spinal Surgery 17(1): 1-6, 2003

 

Epstein NE: Fixed versus dynamic plate complications following multilevel anterior cervical corpectomy and fusion with posterior stabilization. Spinal Cord 41: 379-84,

  2003

 

Epstein NE: Posterior cervical fusion failure in three morbidly obese patients following circumferential surgery. Surgical Neurology, 60:205-210, 2003

 

Epstein NE: Circumferential cervical surgery for Ossification of the Posterior Longitudinal Ligament: A Multianalytic outcome study. Spine, 29 (12):1340-1345, 2004

 

Epstein NE: Dynamic Anterior Cervical  Plates for Multilevel  Anterior Corpectomy  and Fusion With Simultaneous Posterior Wiring and Fusion: Efficacy and Outcomes. Spinal Cord (in press 2005)

 

Epstein NE, Herkowitz HN, Yonenobu Y. Chapter 52: Ossification of the Posterior Longitudinal Ligament. In Spine Surgery: Techniques, Complication Avoidance, and Management 2nd Edition. Benzel EC (ed), Chruchill Livingstone (pub), (in press)

 

Epstein NE: Bennett G: Chapter 58: Ossification of the posterior longitudinal ligament (pg. 729-43. In Spine Surgery: Techniques, Complication Avoidance, and Management, E Benzel (ed), Churchill Livingstone (pub), New York 2005

 

Epstein NE: Circumferential Surgery for ossification of the posterior longitudinal ligament of the cervical spine. In Spine Surgery- Case Studies, Vaccaro AR (ed), Thieme (pub), New York, (in press)

 

Epstein NE: Ossification of the posterior longitudinal ligament. In Textbook Of Neurological Surgery, Batjer H, Loftus C (eds), Lippincott-Raven (pub), Philadelphia PA,  (in press)

 

Operations from the Back of the Neck (Posterior Cervical Surgery)

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Cervical (Neck) Laminotomy For Lateral (Off to the Side) Disc/Arthritis

Removal of a disc located off to one side of the spinal canal is performed in some instances from the back of the neck. This usually requires removing a portion of the bone in the back of the neck (laminotomy) above and below that disc herniation. Disc herniations can be removed utilizing diamond drills for bone removal, and microinstruments under the operating microscope. Spinal cord and nerve root monitoring (SSEP, EMG) employed throughout add to the safety of surgery.

 

Epstein JA, Epstein NE: Complications of cervical laminectomy. How to avoid them, diagnosis and treatment. In Cervical Spine II, H. Sherk (ed), Springer-Verlag (pub), New York, Chapter 3.1: 171-178, 1989

 

Epstein NE: A review of laminoforaminotomy for the management of lateral and foraminal cervical disc herniations or spurs, Surgical Neurology 57(4): 226, 2002

 

Epstein NE: Posterior approaches in the management of cervical spondylosis and ossification of the posterior longitudinal ligament.Surgical Neurology, 58: 194-208,

   2002

 

Epstein NE: Laminectomy for cervical myelopathy. Spinal Cord 41; 317-327, 2003

 

Epstein NE: Posterior Decompression For Radiculopathy: Laminoforaminotomy. Cervical Spine Surgery Atlas, 2nd Edition, Herkowitz H (ed), Lippincott Williams & Wilkins, Chapter 12:157-166, 2004

 

Cervical (Neck) Laminectomy

Patients with compression of the spinal cord over several levels may require a laminectomy. A laminectomy includes removal of bone (the laminae) from the back of the neck. Select older patients with significant arthritic disease or calcified discs in the front of the spine may benefit from this operation if they have a good cervical curvature, and their spine is not straightened or bent forward. Those with arthritic disease behind the spinal cord and a normal spinal curvature can have surgery, performed through the back of the spine.

 

Epstein NE: Myelopathy: Laminectomy, Cervical Spine Research Society Textbook, 4th Edition, Clark CC (ed), Lippincott Williams and Wilkins, (in press)

 

Epstein NE: Cervical Myelopathy: Posterior Approach-Laminectomy. In The Spine, 3rd Edition. Rothman and Simeone (ed), Elsevier (pub), Philadelphia, (in press)

 

Epstein NE: Posterior Decompression For Radiculopathy: Laminoforaminotomy. Cervical Spine Surgery Atlas, 2nd Edition, Herkowitz H (ed), Lippincott Williams & Wilkins, Chapter 12:157-166, 2004

 

Epstein NE: Myelopathy: Laminectomy, Cervical Spine Research Society Textbook, 4th Edition, Clark CC (ed), Lippincott Williams and Wilkins, (in press)

 

Epstein NE: Cervical Myelopathy: Posterior Approach-Laminectomy. In The Spine, 3rd Edition. Rothman and Simeone (ed), Elsevier (pub), Philadelphia, (in press)

 

Cervical (Neck) Laminectomy with Fusion

When patients undergo multilevel laminectomy, fusion may be required. Fusions from the back of the neck can utilize wires alone or rods/eyelets with wires.

 

Epstein NE: Laminectomy with posterior wiring and fusion for cervical OPLL, spondylosis, OYL, stenosis, and instability:  A study of 5 patients.  J Spinal Disord 12: 461-466, 1999

 

Epstein NE: Technical Note: Unilateral posterior resection of cervical disc and spondylostenosis with contralateral fusion for instability, Surgical Neurology 56:

  256-258, 2001

 

Epstein NE: Cervical laminectomy with or without posterior wiring and fusion or laminoplasty for the management of spondylostenosis and ossification of the posterior

   longitudinal ligament, Surgical Neurology, 58: 194-208, 2002

 

Epstein NE. Posterior Cervical Fusion Utilizing A Modified “Screwless” Vertex System  A Preliminary Report in 8 Patients. Spinal Surgery; 18(2): 63-70, 2004

 

Thoracic Spinal Surgery (Mid Back Surgery)

 

Laminectomy (Back) for Thoracic Stenosis

Laminectomy may be required for removal of tumor, decompression of stenosis, or removal of discs from the mid back (thoracic) spine.

 

Epstein NE, Schwall G: Thoracic spinal stenosis: diagnostic and treatment challenges. J Spinal Disord, 7(3): 259-269, 1994

 

Transthoracic (Front of the Mid Back) Surgery For OPLL

 

Epstein NE: Clinical Opinion: Thoracic ossification of the posterior longitudinal ligament, ossification of the yellow ligament from T9-T12, with superimposed acute T10-T11 disc herniation: Controversies in surgical management. J Spinal Disord, 9(5):  466-450, 1996

 

Epstein NE: Transthoracic and transabdominal approach to T9-T12 ossification of the posterior longitudinal ligament with herniated disc/stenosis. In Spine Surgery- Case Studies, Vaccaro AR (ed), Thieme (pub), New York, (in press)

 

Surgery of the Lower Back (Lumbar Surgery)

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Microscope Assisted Diskectomy/Laminotomy

If a disc herniation compresses one specific nerve root and is not accompanied by significant arthritic changes or instability (too much slippage), a microscope-assisted diskectomy may be appropriate. To adequately expose the nerve root and accompanying arthritic changes or stenosis, more bone can be removed (laminotomy, partial laminectomy). Once the pressure is taken off the nerve root (decompressed), the disc space is entered to remove additional loose free fragments and reduce the risk of disc recurrence (another piece of disc popping out). Although “fashionable” (minimally invasive) alternatives are now available, many carry a higher risk of infection and spinal fluid leak. Furthermore, the full extent of disease may not be recognized, limiting the patient’s recovery.

 

Epstein NE, Epstein JA: The surgical management of lumbar foraminal and far lateral herniated discs complicated by vertebral limbus fractures. Neuro-Orthopedics (Springer-Verlag), 17/18: 173-178, 1995

 

Epstein NE: Evaluation of varied surgical approaches used in the management of 170 far lateral lumbar disc herniations: Indications and results. J Neurosurg, 83: 648-656, 1995

 

Epstein NE: Lumbar Laminectomy for the Resection of Synovial Cysts and Coexisting Lumbar Spinal Stenosis or Degenerative Spondylolisthesis: An Outcome Study. Spine

  Spine. 2004 Apr 23;29(9):1049-55.

Complications of Minimally Invasive Approaches

 

Epstein NE: Nerve root complications of percutaneous laser assisted diskectomy performed at outside institutions: A technical report. J Spinal Disord, 7(6): 510-512, 1994

 

Epstein NE: Laser assisted diskectomy performed by an internist resulting in cauda equina syndrome: Technical note. J Spinal Disord, 12(1): 77-79, 1999

 

Partial Laminectomy/Laminectomy (Removal of Bone Behind the Lower Back)

For patients with more extensive arthritic disease of the spine, an operation removing several lower back bones (laminae) may be warranted.  These procedures remove arthritic disease (spur, spondylosis, ossified yellow ligament), provide more room for narrowed spinal canals (decompress stenosis), and may or may not require excision of disc herniations, Together, X-rays, MR, and CT studies define the full extent of arthritic disease. Many of these operations are performed in older patients (50’s-80’s), although a subset born with narrowed spinal canals may develop symptoms earlier (30’s, 40’s). If there is no evidence for abnormal motion between bony levels (no slip, instability), multilevel laminectomy without fusion may be the appropriate operation. Furthermore, if the amount/extent of bone removed during the decompression affects stability, a fusion may be required.

 

Epstein JA, Epstein NE: Lumbar spinal stenosis. In Surgery of the Spine -A combined Orthopedic and Neurosurgical Approach,  GFG Findlay and R. Owens (eds), Blackwell Scientific (pub), Oxford England,  Chapter 41: 719-732, 1992

 

Epstein NE, Hood DC: A comparison of surgeon’s assessment to patient’s self analysis (Short Form 36) after far lateral lumbar disc surgery: An outcome study. Spine, 22(20): 2422-2428, 1997

 

Epstein NE: Surgical management of lumbar stenosis: decompression and indications for fusion. Neurosurg Focus  3(2): Article 1: 1-14, August 1997

 

Epstein NE: Decompression in the surgical management of degenerative spondylolisthesis: Advantages of a conservative approach in 290 patients. J Spinal Disord, 11(2): 116-122, 1998

 

Epstein NE: Foraminal and far lateral disc herinations: Surgical alternatives and outcome measures. Spinal Cord 40: 491-500, 2002

 

Epstein NE: Chapter 55: Surgery for Far Lateral Lumbar Disc Herniations.p.719-738, In Omurilik ve Omurga Cerrahisi, 1st Edition, M Zileli, A.F. Ozer (Eds), Tpian A.S.,

    Medikon A.S., 2002

 

Epstein NE: Chapter 168: Far Lateral Lumbar Disc Herniations: Diagnosis and Surgical Management. In Operative Neurosurgical Techniques, 5th Ed., Schmidek, Sweet.

    Elsevier, 2004

 

Epstein NE: Review Article/Lumbar Synovial Cysts, A Review of Diagnosis, Surgical Management, and Outcome Assessment. J Spinal Disorder Tech, Vol 17(4):321-325,

    August, 2004

 

Laminectomy with Fusion

If patients have evidence that the spine is moving too much (unstable) on X-rays (plain X-rays, flexion/extension views), MR or CT studies, a fusion may be required at the time of surgery. Furthermore, where the operation includes the removal of bone needed for stability, fusions may be warranted. These operations are typically performed in conjunction with single or multilevel laminectomies. Fusions can also be performed form the front or the back of the spine.

 

Non-Instrumented Posterior (Back) Fusion

In select older patients, more rarely younger individuals, non-instrumented lower back (lumbar) fusions may be required. Indications include: (a) massive disc herniation (central), (b) arthritic slip in patient with osteoporosis, (c) patient with cyst popping out of the facet joint (synovial cyst), (d) other. These operations are most typically combined with multilevel laminectomies in older osteoporotic patients and can be performed over multiple levels. They utilize the patients own bone obtained from the laminectomy. Patients are often braced for 3-4 months. CT scans and Flexion/Extension X-rays are utilized to document fusion.

 

Instrumented Fusion Posterior (Back) Fusion

In patients with unstable lumbar spines, instrumented fusions may be required. Indications for fusion are multiple: (a) disc excision particularly in a younger patient resulting in instability, (b) removal of a facet joint, (c) chronic slip in the bones (spondylolisthesis), (d) fracture in the bone between the facet joints (spondylolysis), (e) other. Fusions performed with laminectomy often utilize the bone harvested from the laminectomy (autograft) site and do not typically require bone from the hip (iliac autograft). These operations are performed with monitoring and fluoroscopy. Patients usually wear a body brace from 3-4 months or until fused based on both Flexion/Extension X-rays and CT scans.

 

Epstein NE: Primary fusion for the management of “unstable” degenerative spondylolisthesis. Neuro - Orthopedics (Spinger-Verlag), 23:45-52,1998

 

Epstein NE: Lumbar Synovial Cysts: a review of diagnosis, surgical management, and outcome assessment. J Spinal Disord Tech. 2004 Aug;17(4):321-5.

 

Diagnostic Imaging

X-rays   Plain X-rays of the spine taken from the front (AP or anterior/posterior) or the side (lateral) yield important information regarding the alignment of the spine. Flexion and extension X-rays detail whether there is any abnormal motion (instability) of the spine when the patient flexes forward or extends backward.

 

MR and CT   Identification of spinal disease can be confirmed with both MR and CT studies. MR (Magnetic Resonance Imaging) examinations do not involve radiation. They best document the soft tissues (nerves, spinal cord) of the spine, and the soft-tissue disease compressing the nerve tissue (discs, tumors). On the other hand, CT scans better demonstrate bone detail such as arthritic changes, stenosis (narrowing of the cervical spine), and calcified discs. 

 

Epstein NE: From Postsurgical Imaging: Marked superior and inferior migration of a dynamic plate after multilevel anterior corpectomy and fusion with posterior wiring. The Spine Journal 1: 226, 2001

 

Epstein NE: Computed Tomography (CT) validating bony ingrowth into fibula strut

   allograft: A criteron for fusion, The Spine Journal, 2: 129-133, 2002

 

Epstein NE, Silvergleide RS: Documenting fusion following anterior cervical surgery: A

  comparison of roentgenogram versus two-dimensional computed tomographic findings.

   J Spinal Disorders & Tech 16(3): 243-7, 2003

 

Epstein NE, Rosenthal AD, Epstein JA, Hyman RA: Technical Note: “Dynamic” MRI scanning of the cervical spine. Spine, 13(8): 937-938, 1988

 

Intraoperative Monitoring

The risk of neurological damage during operations on the neck (cervical), mid back (thoracic), and lower back (lumbar spine) can be minimized by utilizing intraoperative monitoring. Somatosensory Evoked Responses (SSEPs) study the electrical potentials in the spinal cord from the hands and feet, through the neck to the brain. If changes occur in these potentials while putting the tube in the throat at the beginning of surgery (intubation), during operative positioning, or during the operation itself, adjustments to help protect the spinal cord can be made. The electrical potentials of the nerves themselves (EMG’s) can also be monitored during selected intervals of operations from the front or back of the spine.

 

Epstein NE: Somatosensory evoked potential monitoring in cervical spine surgery. In Degenerative Disease of the Cervical Spine, Neurosurgical Topics Book Series of the AANS, P Cooper (ed), Robert Wilkins (pub), New York, Chapter 5: 49-72, 1992

 

Epstein NE, Danto J, Nardi D: Evaluation of intraoperative somatosensory evoked potential (SSEP) monitoring during 100 cervical operations. Spine, 18(6): 737-747, 1993

 

Epstein NE: Somatosensory evoked potential monitoring (SSEPs) in 173 cervical operations. Neuro-Orthopedics (Spring-Verlag), 20: 2-21, 1996

 

Epstein NE: Impact of somatosensory evoked potential monitoring on outcomes in cervical surgery. In Principles of Spinal Surgery, Benzel E (ed), McGraw Hill  (pub), New York, (in press)

 

Epstein NE: Intraoperative monitoring for spine surgery (Part A): an aggressive approach to monitoring. In Controversies in Spine Surgery,  Benzel E, Zdeblick T, Anderson P, Stillerman C (eds), Chapter 26 (in press)

 

Bloodless Surgery” or Normovolemic Hemodilution

In conjunction with her colleagues in Anesthesia, Dr. Epstein utilizes “Bloodless Spinal Surgery” in appropriate cases. This technique is particularly useful in lower back (lumbar) surgery performed with or without fusion. It has proven useful in patients whose religious beliefs don’t allow for the use of blood products (i.e. Jehovah’s Witnesses). “Bloodless Surgery” can be utilized in the majority of healthy individuals. Preoperative blood donation is avoided (with its risks of infection, receiving the wrong unit, removal of coagulation factors), along with its cost. At the beginning of surgery, the patient’s blood is removed (1-2 units based on your preoperative blood level); patients are given fluids to maintain a normal blood pressure. During the operation, less blood (fewer red cells) is lost. At the end of surgery, the patient’s fresh blood is returned. Most patients have not required additional blood transfusions.

 

Epstein NE, Peller A, Boutros A, DeCrosta D, Schmigelski C, Greco J.  "Bloodless" Lumbar Decompressions with Instrumented Fusions: A Preliminary Report of 14 Cases. Winthrop University Hospital Medical Journal, 2004

 

Epstein NE, Peller A, Koreff J, DeCrosta D, Boutros A, Schmigelski, C, Greco J:  Normovolemic Hemodilution: An Effective Method for Limiting Postoperative Transfusion Following Complex Lumbar Spinal Decompression with

Instrumented Fusion. Spinal Surgery 18(3):179-188, 2004

 

 

Evaluation of Artificial Bone Substitutes to Avoid Cadaver Graft

Dr. Epstein has recently studied whether artificial bone can be used to expand and supplement bone taken from the patients themselves (autograft) during different types of procedures. Beta Tricalcium Phosphate appears to be just such a promising bone expander.

 

Epstein NE: Efficacy of Combined Beta Tricalcium Phosphate in Anterior Iliac Crest Reconstruction with MacroPore Sheet. Spinal Surgery (in press 2005)